The eight Phase 1 winners were recommended by a judging panel composed of federal employees from across NIH. They were each awarded $100,000 and an exclusive invitation to participate in Phase 2. During Phase 2, these winners will receive access to expert support and additional resources as they iterate on their solutions and conduct proof-of-concept studies.

Anthony F. DiMarco, M.D.

High-frequency spinal cord stimulation reduces respiratory tract infections and improves bowel management in people with neurological impairment.

BIOS Health

The Autonomic Therapy Initiative, data-driven stimulations of the vagus nerve using neural biomarkers, modulates cardiac function and minimizes side effects on off target organs. Learn more about BIOS Health here.

General Electric Research, in collaboration with Northwell Health and Yale University

A single, image-guided ultrasound treatment induces a response in the gut-brain sensory pathway to provide sustained remission in Type 2 diabetes and obesity.

Neuroengineering & Pain Research (NPR) Lab at the University of Connecticut

Synchronized pulse and sinusoidal stimulation of sacral dorsal root ganglia (DRG) and nerve roots relieves chronic visceral pain in the lower abdominal organs by selectively blocking C-fiber neural transmission.

RBI Medical

Ultraprecise, selective pelvic neuromodulation therapy treats stress urinary incontinence, overactive bladder, and fecal incontinence using a minimally invasive micro-implant. Learn more about RBI Medical here.

University of Louisville Research Foundation, Inc.

StimXS, neuromodulation of the lumbosacral spinal cord, automatically regulates cardiovascular, respiratory, and urinary systems after spinal cord injury.

University of Pittsburgh Department of Urology

A multichannel implantable device for sacral-pudendal neuromodulation addresses bladder, bowel, and sexual disorders.

Warren Grill and collaborators, Duke Biomedical Engineering

Electrical recording and stimulation of the sacral nerve with closed-loop bioelectronic control restores bladder and bowel function.